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Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are both chronic conditions with rapidly increasing prevalence and incidence worldwide that have led to a significant burden on health-care systems. An increasing number of different pathogenic mechanisms are influencing the progression of chronic kidney disease. NAFLD is the most frequent cause of chronic liver disease, affecting 30% of the general population, increasing its prevalence in patients with type 2 diabetes mellitus (T2DM) and obesity (70% and 95%, respectively). It is known that NAFLD not only increases the risk of T2DM and cardiovascular disease, but also the incidence of CKD in patients with and without DM. However, the pathological mechanisms leading to the relation between NAFLD and CKD are yet unclear. In recent years, there have been many scientific publications trying to find a link between the two entities. For this reason, it is of great scientific importance to address this pathogenic mechanism in the genesis of CKD.
#26 – Non-Alcoholic Fatty Liver Disease and Chronic Kidney Disease – what is the link