Hot topics in Nephrology

Topic Atypical Haemolytic Uraemic Syndrome

A 41 year old woman with end stage renal failure, secondary to atypical haemolytic uraemic syndrome (aHUS), is being worked up to receive a live donor kidney from her sister. She asks about the likelihood of recurrence of aHUS in her transplanted kidney.

A genetic mutation in which protein is least associated with recurrence of aHUS in the transplanted kidney?