Kidney stones: When to perform a genetic test? How to manage for paediatricians and adult nephrologists?
How to set the stage for a full-fledged clinical trial testing incremental haemodialysis
EuDial Research Project
Elisa Tarrío Herva
Country of Origin:
Spain
Host University:
“Aldo Moro” University of Bari, Italy
Fellowship’s period:
October, 2023 – October, 2024
Activity
Objectives:
- Evaluate residual kidney function preservation in incremental hemodialysis (HD).
- Assess the safety of incremental HD in incident patients.
- Analyze electrolyte disorder control in incremental HD patients
Results:
- Urinary output tends to be better preserved in patients undergoing incremental HD; however, the difference has not yet reached statistical significance and is still early for strong results.
- Still early to confirm the safety of incremental HD. Currently, REAL-LIFE study appears to be safe, if compared mortality and hospitalization rates to other feasibility studies on incremental HD.
- No differences in potassium levels were observed. Hyperphosphatemia has shown a slightly higher prevalence in patients on incremental HD. A higher prevalence of acidosis in incremental HD patients underscores the importance of adequate bicarbonate supplementation.