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Food as medicine in chronic kidney disease

ERN Research Project

Alice Baganha Sabatino

Country of Origin:
Italy

Host University:
Karolinska Institute, Sweden

Fellowship’s period:
September, 2023 – August, 2024

Activity

Objectives:

  • Participation in ongoing projects and involvement in the development of new projects within the research line “Food as medicine in CKD”
  • Development, follow-up, and analysis of a survey investigating the use of Intradialytic Parenteral Nutrition in Europe
  • Revise the ERA Cookbook regarding the adequacy of the recipes and update it.

Results:

The fellowship goals were achieved, and it resulted in my participation in 7 projects and the renewal of my stay in Stockholm. Most of the projects are still ongoing.
The projects are:

  • Myosteatosis and mortality in patients with CKD
  • Intradialytic Parenteral Nutrition in Europe: A survey assessing its use among clinical practitioners
  • Postprandial changes in plasma potassium after the ingestion of a healthy potassium-rich meal in patients with chronic kidney disease
  • The effect of the nutraceutical (-)- Epicatechin on myosteatosis in patients with advanced CKD: a pilot study (EPIC-CKD)
  • Diagnosing malnutrition in patients on dialysis – barriers and facilitators
  • ERA Cookbook
  • The effect of uremia on the clock mechanism of skeletal muscle cells

Publications

ERA Cookbook
https://www.era-online.org/cookbook/about-the-project/

 

Making the invisible visible: imaging techniques for assessing muscle mass and muscle quality in chronic kidney disease
CKJ, March 2024
https://doi.org/10.1093/ckj/sfae028

 

Myosteatosis is associated with ageing, adiposity, poor muscle quality, metabolic derangements and mortality in patients with chronic kidney disease.
To be published soon

 

Food additives containing potassium, phosphorus, and sodium in ultra-processed foods: Potential harms to individuals with CKD.
To be published soon

 

Low muscle strength alone and sarcopenia have a stronger association with mortality than low muscle mass alone in patients on dialysis: Results from a systematic review and meta-analysis.
To be published soon